Zhang RQiao SAggarwal AYuan GMuttau NSharma ALwatula CNgosa LKabwe MManasyan AMenon AOstermann JWeissman SLi XHarper GW2025-05-232024-Feb10.1016/j.apnu.2024.01.004https://pubs.cidrz.org/handle/123456789/10802Sexual minority men (SMM) in Zambia face significant challenges including stigma, discrimination, and mental health issues, which further impact their HIV-related risk behaviors. This study aimed to investigate the associations between enacted stigma, substance abuse, HIV-related behaviors, and mental health (i.e., depression, anxiety, and post-traumatic stress disorder [PTSD] symptoms) among SMM in Zambia. SMM aged 18-35 years who reported having multiple and/or concurrent sexual partners or low and/or inconsistent condom use in the past three months were recruited from four districts in Zambia between February and November 2021. Participants completed an anonymous interviewer-administered survey. Key variables of interest were compared between participants with higher vs. lower levels of enacted stigma. Independent samples t-tests were used for continuous variables, and chi-squared tests were used for categorical variables. A total of 197 eligible SMM participated in the study (mean age = 24.41 years). Participants with a higher level of enacted stigma showed a higher level of anxiety symptoms (χImpact of enacted stigma on mental health, substance use, and HIV-related behaviors among sexual minority men in Zambia.