Browsing by Author "Michelo C"

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    How we implemented an analytical support clinic to strengthen student research capacity in Zambia.
    (2015-Jul) Andrews B; Musonda P; Simuyemba M; Wilson CM; Nzala S; Vermund SH; Michelo C; b University of Zambia , Zambia.; d East Anglia University , UK.; c Centre for Infectious Disease Research in Zambia (CIDRZ) , Zambia.; a Vanderbilt University , USA.; e University of Alabama at Birmingham , USA.
    BACKGROUND: Research outputs in sub-Saharan Africa may be limited by a scarcity of clinical research expertise. In Zambia, clinical and biomedical postgraduate students are often delayed in graduation due to challenges in completing their research dissertations. We sought to strengthen institutional research capacity by supporting student and faculty researchers through weekly epidemiology and biostatistics clinics. METHODS: We instituted a weekly Analytical Support Clinic at the University of Zambia, School of Medicine. A combination of biostatisticians, clinical researchers and epidemiologists meet weekly with clients to address questions of proposal development, data management and analysis. Clinic sign-in sheets were reviewed. RESULTS: 109 students and faculty members accounted for 197 visits to the Clinic. Nearly all clients (107/109, 98.2%) were undergraduate or postgraduate students. Reasons for attending the Clinic were primarily for proposal development (46.7%) and data management/analysis (42.1%). The most common specific reasons for seeking help were data analysis and interpretation (36.5%), development of study design and research questions (26.9%) and sample size calculation (21.8%). CONCLUSIONS: The Analytical Support Clinic is an important vehicle for strengthening postgraduate research through one-on-one and small group demand-driven interactions. The clinic approach supplements mentorship from departmental supervisors, providing specific expertise and contextual teaching.
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    Risk factors for impaired fasting glucose or diabetes among HIV infected patients on ART in the Copperbelt Province of Zambia.
    (2017) Shankalala P; Jacobs C; Bosomprah S; Vinikoor M; Katayamoyo P; Michelo C; Department of Biostatistics, School of Public Health, University of Ghana, Accra, Ghana.; School of Public Health, Department of Epidemiology and Biostatiscs, University of Zambia, P.O Box 5110, Lusaka, Zambia.; Department of Medicine, University of Alabama at Birmingham, Birmingham, USA.; Centre for Infectious Diseases Research in Zambia, 5032 Great North Road, Lusaka, Zambia.; Family Health International (fhi360), Plot 2374, Farmers Village, ZNFU Complex, Showground's Area, TiyendePamodzi Road, Off Nangwenya Road, P.O. Box 320303, Lusaka, Zambia.; CIDRZ; Centre for Infectious Disease Research in Zambia (CIDRZ)
    BACKGROUND: Africa has a high prevalence of both Human Immunodeficiency Virus and Non Communicable Diseases (NCDs) but in Zambia there are few data on co-morbid NCDs like Diabetes Mellitus (DM) among HIV-infected individuals. We aimed to identify risk factors for impaired fasting glucose or diabetes among HIV-infected Zambians on long-term Combined Antiretroviral Treatment (cART). METHODS: This was a cross sectional study of adult HIV patients in five health facilities of Copperbelt Province in Zambia. HIV/AIDS patients aged 18 years and above, enrolled in care at those health facilities and had been on cART for more than 2 years were included. All patients known to have Diabetes mellitus were excluded from the study. Participants underwent assessment of random blood sugar levels at enrolment and returned the following morning for fasting glucose measured by glucometers. The primary outcome was proportion with impaired fasting glucose or DM. Multivariable logistic regression was used to examine if demographics, time on ART, type of ART regimen, body mass index and baseline CD4 count were predictors of impaired fasting glucose. RESULTS: Overall ( CONCLUSION: We have found high levels of impaired fasting glucose or diabetes among ART patients compared to what is reported in the general population suggesting missed care and support opportunities associated with metabolic imbalance management. There is thus a need to re-package HIV programming to include integration of diabetes screening as part of the overall care and support strategy.