High Unreported Mortality in Children and Youth (<25 Years) Living With HIV Who Were Lost to Care From Antiretroviral Therapy Programs in Southern Africa: Results From a Multicountry Tracing Study.

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dc.contributor.affiliationInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
dc.contributor.affiliationNewlands Clinic, Harare, Zimbabwe.
dc.contributor.affiliationWellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine.
dc.contributor.affiliationSolidarMed, Maseru, Lesotho.
dc.contributor.affiliationCentre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa.
dc.contributor.affiliationCentre for Infectious Diseases Research in Zambia, Lusaka, Zambia.
dc.contributor.affiliationLighthouse Trust Clinic, Lilongwe, Malawi.
dc.contributor.affiliationSolidarMed, Pemba, Mozambique.
dc.contributor.affiliationSolidarMed, Masvingo, Zimbabwe.
dc.contributor.affiliationR.M. Fairbanks School of Public Health, Department of Biostatistics, Indiana University, Indianapolis, IN; and.
dc.contributor.affiliationDignitas International, Zomba, Malawi.
dc.contributor.affiliationDepartment of Statistics, Ludwig-Maximilians-Universität München, München, Germany.
dc.contributor.affiliationCIDRZ
dc.contributor.affiliationCentre for Infectious Disease Research in Zambia (CIDRZ)
dc.contributor.authorNyakato P
dc.contributor.authorChrist B
dc.contributor.authorAnderegg N
dc.contributor.authorMuhairwe J
dc.contributor.authorJefferys L
dc.contributor.authorvan Dijk J
dc.contributor.authorVinikoor MJ
dc.contributor.authorvan Lettow M
dc.contributor.authorChimbetete C
dc.contributor.authorPhiri SJ
dc.contributor.authorEgger M
dc.contributor.authorBallif M
dc.contributor.authorYiannoutsos CT
dc.contributor.authorSchomaker M
dc.contributor.authorKassanjee R
dc.contributor.authorDavies MA
dc.contributor.authorCornell M
dc.date.accessioned2025-05-23T11:40:45Z
dc.date.issued2022-Dec-15
dc.description.abstractBACKGROUND: Antiretroviral therapy program mortality maybe underestimated if deceased patients are misclassified as lost. METHODS: We used two-stage inverse probability weighting to account for probability of being: sampled for tracing and found by the tracer. RESULTS: Among 680 children and youth aged <25 years on antiretroviral therapy who were lost and traced in Southern Africa between October 2017 and November 2019, estimated mortality was high at 9.1% (62/680). After adjusting for measured covariates and within-site clustering, mortality remained lower for young adults aged 20-24 years compared with infants aged <2 years [adjusted hazard ratio: 0.40 (95% confidence interval: 0.31 to 0.51)]. CONCLUSIONS: Our study confirms high unreported mortality in children and youth who are lost and the need for tracing to assess vital status among those who are lost to accurately report on program mortality.
dc.identifier.doi10.1097/QAI.0000000000003090
dc.identifier.urihttps://pubs.cidrz.org/handle/123456789/10292
dc.sourceJournal of acquired immune deficiency syndromes (1999)
dc.titleHigh Unreported Mortality in Children and Youth (<25 Years) Living With HIV Who Were Lost to Care From Antiretroviral Therapy Programs in Southern Africa: Results From a Multicountry Tracing Study.

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