Six-month hemoglobin concentration and its association with subsequent mortality among adults on antiretroviral therapy in Lusaka, Zambia.

Simple item page
dc.contributor.affiliationCentre for Infectious Disease Research in Zambia, Lusaka, Zambia. giganticidrz@gmail.com
dc.contributor.affiliationCIDRZ
dc.contributor.affiliationCentre for Infectious Disease Research in Zambia (CIDRZ)
dc.contributor.authorGiganti MJ
dc.contributor.authorLimbada M
dc.contributor.authorMwango A
dc.contributor.authorMoyo C
dc.contributor.authorMulenga LB
dc.contributor.authorGuffey MB
dc.contributor.authorMulenga PL
dc.contributor.authorBolton-Moore C
dc.contributor.authorStringer JS
dc.contributor.authorChi BH
dc.date.accessioned2025-05-23T11:42:35Z
dc.date.issued2012-Sep-01
dc.description.abstractLittle is known about changes in hemoglobin concentration early in the course of antiretroviral therapy and its subsequent relation to survival. We analyzed data for 40,410 HIV-infected adults on antiretroviral therapy in Lusaka, Zambia. Our main exposure of interest was 6-month hemoglobin, but we stratified our analysis by baseline hemoglobin to allow for potential effect modification. Patients with a 6-month hemoglobin <8.5 g/dL, regardless of baseline, had the highest hazard for death after 6 months (hazard ratio: 4.5; 95% confidence interval: 3.3 to 6.3). Future work should look to identify causes of anemia in settings such as ours and evaluate strategies for more timely diagnosis and treatment.
dc.identifier.doi10.1097/QAI.0b013e31825da11d
dc.identifier.urihttps://pubs.cidrz.org/handle/123456789/10695
dc.sourceJournal of acquired immune deficiency syndromes (1999)
dc.titleSix-month hemoglobin concentration and its association with subsequent mortality among adults on antiretroviral therapy in Lusaka, Zambia.

Files

Original bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
article.pdf
Size:
849.84 KB
Format:
Adobe Portable Document Format
Download

Collections

Published