Delivery of TB preventive therapy to incarcerated people living with HIV in southern African correctional facilities.

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dc.contributor.authorChimoyi L
dc.contributor.authorSmith H
dc.contributor.authorHausler H
dc.contributor.authorFielding K
dc.contributor.authorHoffmann CJ
dc.contributor.authorHerce ME
dc.contributor.authorCharalambous S
dc.date.accessioned2025-09-17T10:25:56Z
dc.date.issued2021-Dec-21
dc.description.abstractTB preventive treatment (TPT) is recommended for high-risk and hard-to-reach populations such as incarcerated people living with HIV (PLHIV). To assess implementation of TPT delivery in correctional settings, we conducted an exploratory analysis of data from a multisite cohort study in South Africa and Zambia. From 975 participants, 648 were screened for TB, and 409 initiated TPT mostly within a month after initiation of antiretroviral therapy (190/409, 46.5%). We observed a median gap of one month (IQR 0.6-4.7) in TPT delivery to incarcerated PLHIV. Future research should examine standardised quality improvement tools and new strategies such as short-course regimens to improve TPT initiation in this population.
dc.identifier.doi10.5588/pha.21.0056
dc.identifier.urihttps://pubs.cidrz.org/handle/123456789/11951
dc.identifier.uri.pubmedhttps://pubmed.ncbi.nlm.nih.gov/34956843/
dc.relation.affiliationThe Aurum Institute, Parktown, Johannesburg, South Africa.
dc.relation.affiliationCentre for Infectious Disease Research in Zambia (CIDRZ)
dc.relation.affiliationSchool of Population Health, University of New South Wales, Sydney, NSW, Australia.
dc.relation.affiliationTB HIV Care, Cape Town, South Africa.
dc.relation.affiliationLondon School of Tropical Hygiene & Medicine, London, UK.
dc.relation.affiliationThe Aurum Institute, Parktown, Johannesburg, South Africa.
dc.relation.affiliationJohns Hopkins University, Baltimore, MD, USA.
dc.relation.affiliationCentre for Infectious Disease Research in Zambia (CIDRZ)
dc.relation.affiliationInstitute for Global Health & Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
dc.relation.affiliationThe Aurum Institute, Parktown, Johannesburg, South Africa.
dc.relation.affiliationSchool of Public Health, University of the Witwatersrand, Johannesburg, South Africa.
dc.sourcePublic health action
dc.titleDelivery of TB preventive therapy to incarcerated people living with HIV in southern African correctional facilities.

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