Cognitive impairment and psychiatric morbidity in HIV+ Zambians with new-onset seizure.

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dc.contributor.authorKalungwana, Lisa
dc.contributor.authorElafros, Melissa A.
dc.contributor.authorSiddiqi, Omar K.
dc.contributor.authorBositis, Christopher M.
dc.contributor.authorSikazwe, Izukanji
dc.contributor.authorKoralnik, Igor J.
dc.contributor.authorTheodore, William H.
dc.contributor.authorBirbeck, Gretchen L.
dc.date.accessioned2025-09-17T10:27:35Z
dc.date.issued2014-Dec
dc.description.abstractA prospective cohort study of new-onset seizure in people with human immunodeficiency virus (HIV) in Zambia is ongoing to determine the incidence of subsequent epilepsy and risk factors for epileptogenesis in this population. At enrollment, we evaluated this cohort for cognitive impairment and psychiatric morbidity. Over 50% of participants had cognitive impairment and significant psychiatric morbidity. Most participants had advanced HIV disease based on CD4+ T-cell count and World Health Organization stage, but we found no association between cognitive impairment or psychiatric morbidity and HIV disease staging.
dc.identifier.doi10.4269/ajtmh.13-0758
dc.identifier.urihttps://pubs.cidrz.org/handle/123456789/12274
dc.identifier.uri.pubmedhttps://pubmed.ncbi.nlm.nih.gov/25311691/
dc.relation.affiliationCentre for Infectious Disease Research in Zambia (CIDRZ)
dc.relation.affiliationCentre for Infectious Disease Research in Zambia (CIDRZ)
dc.relation.affiliationCentre for Infectious Disease Research in Zambia (CIDRZ)
dc.relation.affiliationCentre for Infectious Disease Research in Zambia (CIDRZ)
dc.relation.affiliationCentre for Infectious Disease Research in Zambia (CIDRZ)
dc.relation.affiliationCentre for Infectious Disease Research in Zambia (CIDRZ)
dc.relation.affiliationCentre for Infectious Disease Research in Zambia (CIDRZ)
dc.relation.affiliationCentre for Infectious Disease Research in Zambia (CIDRZ)
dc.sourceThe American journal of tropical medicine and hygiene
dc.titleCognitive impairment and psychiatric morbidity in HIV+ Zambians with new-onset seizure.

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